Clinical study of the 1CU accommodating intraocular lens☆

Abstract 

Purpose

To compare the near functional capacities of patients with an accommodating intraocular lens (IOL) with those of patients with a conventional monofocal IOL.

Setting

Department of Ophthalmology, University of Chieti, Chieti, Italy.

Methods

This prospective double-blind case-control study comprised 42 eyes that had phacoemulsification and implantation of 1 of 2 types of IOLs: HumanOptics accommodating 1CU® (study group) and Eurocrystal IFP 3G 6.00 (control group). The main outcome measures were subjective refraction, uncorrected distance acuity, best corrected distance acuity, distance corrected near acuity at 40 cm, best corrected near acuity at 40 cm, and subjective amplitude of accommodation. Patients were examined 7, 30, 90, and 180 days after surgery.

Results

Postoperatively, both groups had excellent uncorrected distance acuity, best corrected distance acuity, and best corrected near acuity. In the study group, the mean distance corrected near acuity (Jaeger) was 5.43 ± 0.98 (SD) (range 4 to 7) at 7 days, 2.33 ± 0.48 (range 2 to 3) at 1 and 3 months, and 3.66 ± 2.12 (range 2 to 7) at 6 months. In the control group, the mean distance corrected near acuity was 7.43 ± 0.50 (range 7 to 8) during the entire follow-up. The differences between the groups was statistically significant (P<.001). The mean amplitude of accommodation was 0.00 diopter (D) in the control group and 1.14 ± 0.44 D (range 0.75 to 2.00 D) in the study group at 7 days, 2.36 ± 0.28 D (range 2.00 to 2.75 D) at 30 and 90 days, and 1.90 ± 0.77 D (range 0.75 to 2.75 D) at 6 months.

Conclusions

The 1CU accommodating IOL provided better useful spectacle-free near visual acuity than the conventional monofocal IOL. However, the accommodating mechanism can play a role in capsule fibrosis.