Late postoperative opacification of MemoryLens hydrophilic acrylic intraocular lenses Case series and review

Tehrani, Mana; Mamalis, Nick; Wallin, Trevin; Dick, H.Burkhard; Stoffelns, Bernhard M; Olson, Randall; Fry, Luther L; Clifford, William S

doi:10.1016/S0886-3350(03)00461-9

« Previous Next »Journal of Cataract & Refractive Surgery
Volume 30, Issue 1 , Pages 115-122, January 2004

Late postoperative opacification of MemoryLens hydrophilic acrylic intraocular lenses Case series and review☆☆☆★★★

Mana Tehrani, MD
- Reprint requests to Mana Tehrani, MD, Johannes Gutenberg-University, Department of Ophthalmology, Langenbeckstrasse 1, 55131 Mainz, Germany.
- Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany
Nick Mamalis, MD
- John A. Moran Eye Center, University of Utah Health Sciences Center, Garden City, KS, USA
Trevin Wallin, MD
- John A. Moran Eye Center, University of Utah Health Sciences Center, Garden City, KS, USA
H.Burkhard Dick, MD
- Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany
Bernhard M Stoffelns, MD
- Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany
Randall Olson, MD
- John A. Moran Eye Center, University of Utah Health Sciences Center, Garden City, KS, USA
Luther L Fry, MD
- Salt Lake City, Utah, and Fry Eye Associates, Garden City, KS, USA
William S Clifford, MD
- Salt Lake City, Utah, and Fry Eye Associates, Garden City, KS, USA

Accepted 23 April 2003.

Abstract

Purpose: To report clinical and spectrographic analyses of 2 explanted hydrophilic acrylic intraocular lenses (IOLs).

Setting: John A. Moran Eye Center, Salt Lake City, Utah, USA, and Johannes Gutenberg-University, Department of Ophthalmology, Mainz, Germany.

Methods: We report 6 cases of opacification of MemoryLens^® IOLs (Ciba Vision) that occurred approximately 2 years after implantation. The anterior and posterior surfaces of the IOLs had a white, frosted appearance, and the IOLs' interior looked brown, similar to the appearance of a brunescent cataract. Two of the IOLs were explanted because of a significant decrease in visual acuity. The IOLs were sent for further clinicopathologic analysis including scanning electron microscopy and energy dispersive x-ray spectroscopy (EDX).

Results: Microscopic analysis revealed multiple, fine, granular deposits of various sizes on the surface of the lens optics. The EDX analysis showed the presence of calcium within the deposits.

Conclusions: Our cases show that hydrophilic acrylic IOLs can opacify even years after implantation. Analysis of the explanted IOLs revealed calcification.

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☆ Presented at the XXth Congress of the European Society of Cataract & Refractive Surgeons, Nice, France, September 2002.

☆☆ Supported in part by a grant from Research to Prevent Blindness, New York, New York, to the Department of Ophthalmology and Visual Sciences, University of the Utah.

★ None of the authors has a financial or proprietary interest in any material or method mentioned.

★★ Drs. David Castner and Dan Graham, senior fellow, Department of Bioengineering, University of Washington, Seattle, Washington, USA, analyzed the IOLs' composition.

PII: S0886-3350(03)00461-9

doi:10.1016/S0886-3350(03)00461-9