Journal of Cataract & Refractive Surgery
Volume 30, Issue 1 , Pages 123-126 , January 2004

Intraindividual comparison of epithelial defects during laser in situ keratomileusis using standard and zero-compression Hansatome microkeratome heads

,Accepted 13 May 2003.

References 

  1. Mirshahi A, Bühren J, Kohnen T. Clinical course of severe central epithelial defects in laser in situ keratomileusis. In press, J Cataract Refract Surg
  2. Dastgheib KA, Clinch TE, Manche EE, et al.  Sloughing of corneal epithelium and wound healing complications associated with laser in situ keratomileusis in patients with epithelial basement membrane dystrophy. Am J Ophthalmol. 2000;130:297–303
  3. Shah MN, Misra M, Wilhelmus KR, Koch DD. Diffuse lamellar keratitis associated with epithelial defects after laser in situ keratomileusis. J Cataract Refract Surg. 2000;26:1312–1318
  4. Møller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Corneal haze development after PRK is regulated by volume of stromal tissue removal. Cornea. 1998;17:627–639
  5. Nakamura K, Kurosaka D, Bissen-Miyajima H, Tsubota K. Intact corneal epithelium is essential for the prevention of stromal haze after laser assisted in situ keratomileusis. Br J Ophthalmol. 2001;85:209–213
  6. Bühren J, Kohnen T. Corneal wound healing after laser in situ keratomileusis flap lift and epithelial abrasion. J Cataract Refract Surg. 2003;29:2007−2012
  7. Bashour M. Risk factors for epithelial erosions in laser in situ keratomileusis. J Cataract Refract Surg. 2002;28:1780–1788
  8. Tekwani NH, Huang D. Risk factors for intraoperative epithelial defect in laser in-situ keratomileusis. Am J Ophthalmol. 2002;134:311–316
  9. Bowker AH. A test for symmetry in contingency tables. J Am Stat Ass. 1948;43:572–574
  10. McNemar Q. Note on sampling error of the differences between correlated proportions or percentages. Psychometrika. 1947;12:153–154
  11. Wilson SE, Mohan RR, Hong J-W, et al.  The wound healing response after laser in situ keratomileusis and photorefractive keratectomy; elusive control of biological variability and effect on custom laser vision correction. Arch Ophthalmol. 2001;119:889–896
  12. Ahee JA, Kaufman SC, Samuel MA, et al.  Decreased incidence of epithelial defects during laser in situ keratomileusis using intraoperative nonpreserved carboxymethylcellulose sodium 0.5% solution. J Cataract Refract Surg. 2002;28:1651–1654

 Supported by a research grant from Bausch & Lomb, Munich, Germany.

☆☆ Dr. Kohnen is a consultant to Bausch & Lomb. None of the other authors has a proprietary or financial interest in any device mentioned.

 Hanns Ackermann, PhD, Institute for Statistics, Johann Wolfgang Goethe-University, assisted in the statistical evaluation of the study and Gerd W.K. Steinkamp, MD, performed some of the LASIK procedures.

PII: S0886-3350(03)00657-6

doi: 10.1016/S0886-3350(03)00657-6

Journal of Cataract & Refractive Surgery
Volume 30, Issue 1 , Pages 123-126 , January 2004