Journal of Cataract & Refractive Surgery
Volume 32, Issue 11 , Pages 1836-1842, November 2006

High-speed optical coherence tomography for management after laser in situ keratomileusis

From the Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA

Accepted 24 July 2006.

Purpose

To report applications of optical coherence tomography (OCT) in the management of laser in situ keratomileusis (LASIK) related problems.

Setting

Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Methods

Five patients referred for LASIK-related problems were enrolled in a prospective observational study. Clinical examination, ultrasound (US) pachymetry, Placido ring slit-scanning corneal topography (Orbscan II, Bausch & Lomb), and high-speed corneal OCT were performed.

Results

In cases of regression and keratectasia, OCT provided thickness measurements of the cornea, flap, and posterior stromal bed. Locations of tissue loss and flap interface planes were identified in a case with a recut enhancement complication. The information was used to determine whether further laser ablation was safe, confirm keratectasia, and manage complications. Optical coherence tomography measurements of central corneal thickness agreed well with US pachymetry measurements (difference 6.4 μm ± 11.7 [SD]) (P = .026), while Orbscan significantly underestimated corneal thickness (−67.5 ± 72.5 μm) (P = .17).

Conclusions

High-speed OCT provided noncontact imaging and measurement of LASIK anatomy. It was useful in monitoring LASIK results and evaluating complications.

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 Supported by grants from NIH (R01 EY013516 and P30 EY03040), Research to Prevent Blindness, Inc., and Carl Zeiss Meditec, Inc.Dr. Huang has a patent royalty interest in optical coherence tomography technology. Drs. Huang and Li receive research grant support from Carl Zeiss Meditec Inc. Drs. Avila and Song have no financial or proprietary interest in any material or method mentioned.

PII: S0886-3350(06)01040-6

doi:10.1016/j.jcrs.2006.07.015

Journal of Cataract & Refractive Surgery
Volume 32, Issue 11 , Pages 1836-1842, November 2006