Journal of Cataract & Refractive Surgery
Volume 32, Issue 11 , Pages 1870-1876, November 2006

Combined Artemis very high-frequency digital ultrasound-assisted transepithelial phototherapeutic keratectomy and wavefront-guided treatment following multiple corneal refractive procedures

  • Dan Z. Reinstein, MD, MA(Cantab), FRCSC

      Affiliations

    • Corresponding Author InformationCorresponding author: Dan Z. Reinstein, MD MA(Cantab), FRCSC, London Vision Clinic, 8 Devonshire Place, London, W1G 6HP, United Kingdom.
  • ,
  • Timothy Archer, Dip Comp Sci(Cantab)

From London Vision Clinic (Reinstein, Archer) and St. Thomas' Hospital–Kings College (Reinstein), London, United Kingdom; Weill Medical College (Reinstein), Cornell University, New York, New York, USA; and Centre Hospitalier National Ophtalmologie (Reinstein), Paris, France

Accepted 28 July 2006.

We present a patient with severe visual symptoms following multiple corneal refractive procedures including automated lamellar keratoplasty, arcuate keratotomy, laser in situ keratomileusis (LASIK), LASIK enhancement by cutting another flap, followed by a further LASIK enhancement by flap lifting. Topography was irregularly irregular, and the best spectacle-corrected visual acuity (BSCVA) was 20/25. Artemis very high-frequency digital ultrasound (US) analysis of the anatomical irregularities of the epithelium and stroma was used in conjunction with the topography to determine the cause of the visual symptoms. Very high-frequency digital US-assisted transepithelial phototherapeutic keratectomy together with a wavefront-guided treatment was used to reduce the stromal surface irregularities and the higher-order aberrations (HOAs), respectively. The treatment successfully regularized the stromal surface, dramatically reduced the HOAs, improved the contrast sensitivity to the high normal range, and improved the BSCVA to 20/20.

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 Dr. Reinstein has a proprietary interest in the Artemis technology (Ultralink LLC) through patents administered by the Cornell Research Foundation, Ithaca, NY. Dr. Reinstein is a consultant for Carl Zeiss Meditec. None of the other authors has a proprietary or financial interest in the materials presented.Preparation in part fulfillment of the requirements for the doctoral thesis, University of Cambridge, for Dr. Reinstein.

PII: S0886-3350(06)01046-7

doi:10.1016/j.jcrs.2006.07.016

Journal of Cataract & Refractive Surgery
Volume 32, Issue 11 , Pages 1870-1876, November 2006