Journal of Cataract & Refractive Surgery
Volume 33, Issue 1 , Pages 59-62 , January 2007

Aqueous humor penetration of gatifloxacin and moxifloxacin eyedrops given by different methods before cataract surgery

  • Lindsay Ong-Tone, FRCSC

      Affiliations

    • Corresponding Author InformationCorresponding author: Dr. Lindsay Ong-Tone, Suite 215, 2125 11th Avenue, Regina, S4P 3X3, Saskatchewan, Canada.

,Accepted 1 September 2006.

References 

  1. Ong-Tone L. Use of a wick to deliver preoperative mydriatics for cataract surgery. J Cataract Refract Surg. 2003;29:2060–2062
  2. Leaming DV. Practice styles and preferences of ASCRS members—2002 survey. J Cataract Refract Surg. 2003;29:1412–1420
  3. Kowalski RP, Karenchak LM, Romanowski EG. Infectious disease: changing antibiotic susceptibility. Ophthalmol Clin North Am. 2003;16(1):1–9
  4. Levine JM, Noecker RJ, Lane LC, et al. Comparative penetration of moxifloxacin and gatifloxacin in rabbit aqueous humor after topical dosing. J Cataract Refract Surg. 2004;30:2177–2182
  5. Hariprasad SM, Mieler WF, Shah GK, et al. Human intraocular penetration pharmacokinetics of moxifloxacin 0.5% via topical and collagen shield routes of administration. Trans Am Ophthalmol Soc. 2004;102:149–155discussion, 155–157
  6. Kim DH, Stark WJ, O'Brien TP. Ocular penetration of moxifloxacin 0.5% and gatifloxacin 0.3% ophthalmic solutions into aqueous humor following topical administration prior to routine cataract surgery. Curr Med Res Opin. 2005;21(1):93–94
  7. Leaming DV. Practice styles and preferences of ASCRS members—2003 survey. J Cataract Refract Surg. 2004;30:892–900
  8. Mather R, Karenchak LM, Romanowski EG, Kowalski RP. Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. Am J Ophthalmol. 2002;133:463–466

 Presented at the ASCRS Symposium on Cataract, IOL and Refractive Surgery, San Francisco, California, USA, March 2006, and the 13th annual meeting of the Canadian Society of Cataract and Refractive Surgery, Montreal, Quebec, Canada, April 2006.Partly funded by Advanced Medical Optics, Markham, Ontario, Canada.The author has no financial or proprietary interest in any method or material mentioned.The Saskatchewan Provincial Laboratory, Regina, Saskatchewan, Canada, provided analysis of the samples, and the Research and Performance Support staff, Regina Qu'Appelle Health Region, Regina, Saskatchewan, Canada, provided analysis of the data.

PII: S0886-3350(06)01218-1

doi: 10.1016/j.jcrs.2006.09.015

Journal of Cataract & Refractive Surgery
Volume 33, Issue 1 , Pages 59-62 , January 2007