Journal of Cataract & Refractive Surgery
Volume 33, Issue 9 , Pages 1546-1549 , September 2007

Incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated with nepafenac

,Accepted 12 May 2007.

References 

  1. Flach AJ. The incidence, pathogenesis, and treatment of cystoid macular edema following cataract surgery. Trans Am Ophthalmol Soc. 1988;96:557–634Available at: http://www.pubmedcentral.nih.gov/tocrender.fcgi?iid=124633Accessed May 23, 2007
  2. Rossetti L, Chaudhuri J, Dickersin K. Medical prophylaxis and treatment of cystoid macular edema after cataract surgery; the results of a meta-analysis. Ophthalmology. 1998;105:397–405
  3. Ginsburg AP, Cheetham JK, DeGryse RE, Abelson M. Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity. J Cataract Refract Surg. 1995;21:82–92
  4. O'Brien TP. Emerging guidelines for use of NSAID therapy to optimized cataract surgery patient care. Curr Med Res Opin. 2005;21:1131–1137erratum, 1431–1432
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  8. Flach AJ. Topical nonsteroidal anti-inflammatory drugs in ophthalmology. Int Ophthalmol Clin. 2002;42(1):1–11
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  10. Yannuzzi LA, Landau AN, Turtz AI. Incidence of aphakic cystoid macular edema with the use of topical indomethacin. Ophthalmology. 1981;88:947–953discussion by ML Klein, 954–954
  11. Kraff MC, Sanders DR, Jampol LM, et al. Prophylaxis of pseudophakic macular edema with topical indomethacin. Ophthalmology. 1982;89:885–890
  12. Flach AJ, Stegmann RC, Graham J, Kruger LP. Prophylaxis of aphakic cystoid macular edema without corticosteroids; a paired-comparison, placebo-controlled double-masked study. Ophthalmology. 1990;97:1253–1258
  13. Solomon LD. Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema; the Flurbiprofen-CME Study Group I. J Cataract Refract Surg. 1995;21:73–81
  14. Miyake K, Masuda K, Shirato S, et al. Comparison of diclofenac and fluorometholone in preventing cystoid macular edema after small incision cataract surgery: a multicentered prospective trial. Jpn J Ophthalmol. 2000;44:58–67
  15. Rossetti L, Bujtar E, Castoldi D, et al. Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery. J Refract Surg. 1996;22:794–799
  16. Italian Diclofenac Study Group . Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema. J Cataract Refract Surg. 1997;23:1183–1189
  17. Donnenfeld ED, Perry HD, Wittpenn JR, et al. Preoperative ketorolac tromethamine 0.4% in phacoemulsification outcomes: pharmacokinetic-response curve. J Cataract Refract Surg. 2006;32:1474–1482
  18. Ke T-L, Graff G, Spellman JM, Yanni JM. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: II. In vitro bioactivation and permeation of external ocular barriers. Inflammation. 2000;24:371–384

 Dr. Braunstein is a paid speaker for Alcon. No author has a financial or proprietary interest in any material or method mentioned.

PII: S0886-3350(07)01025-5

doi: 10.1016/j.jcrs.2007.05.018

Journal of Cataract & Refractive Surgery
Volume 33, Issue 9 , Pages 1546-1549 , September 2007

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