Journal of Cataract & Refractive Surgery
Volume 35, Issue 8 , Pages 1363-1366 , August 2009

Penetration of riboflavin and postoperative pain in corneal collagen crosslinking: Excimer laser superficial versus mechanical full-thickness epithelial removal

Received 23 February 2009 ,Revised 17 March 2009 ,Accepted 18 March 2009.

References 

  1. Wittig-Silva C, Whiting M, Lamoureux E, Lindsay RG, Sullivan LJ, Snibson GR. A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results. J Refract Surg. 2008;24:S720–S725
  2. Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620–627
  3. Wollensak G. Crosslinking treatment of progressive keratoconus: new hope. Curr Opin Ophthalmol. 2006;17:356–360
  4. Spoerl E, Mrochen M, Sliney D, Trokel S, Seiler T. Safety of UVA–riboflavin cross-linking of the cornea. Cornea. 2007;26:385–389
  5. Nishida T. Cornea. In:  Krachmer JH,  Mannis MJ,  Holland EJ editor. Cornea. 2nd ed. Philadelphia, PA: Elsevier Mosby; 2005;p. 4–5
  6. Farquhar MG, Palade GE. Junctional complexes in various epithelia. J Cell Biol. 1963;17:375–412Available at: http://jcb.rupress.org/cgi/reprint/17/2/375Accessed April 26, 2009
  7. McLaughlin BJ, Caldwell RB, Sasaki Y, Wood TO. Freeze-fracture quantitative comparison of rabbit corneal epithelial and endothelial membranes. Curr Eye Res. 1985;4:951–961
  8. Chan CCK, Sharma M, Boxer Wachler BS. Effect of inferior-segment Intacs with and without C3-R on keratoconus. J Cataract Refract Surg. 2007;33:75–80
  9. Hayes S, O'Brart DP, Lamdin LS, Doutch J, Samaras K, Marshall J, et al. Effect of complete epithelial debridement before riboflavin–ultraviolet-A corneal collagen crosslinking therapy. J Cataract Refract Surg. 2008;34:657–661
  10. Yuen L, Chan C, Boxer Wachler BS. Effect of epithelial debridement in corneal collagen crosslinking therapy in porcine and human eyes [letter. J Cataract Refract Surg. 2008;34:1815–1816reply by S Hayes, DP O'Brart, 1816
  11. Müller LJ, Marfurt CF, Kruse F, Tervo TMT. Corneal nerves: structure, contents and function. Exp Eye Res. 2003;76:521–542errata 2003; 77:253
  12. Oliveira-Soto L, Efron N. Morphology of corneal nerves using confocal microscopy. Cornea. 2001;20:374–384
  13. Wewers ME, Lowe NK. A critical review of visual analogue scales in the measurement of clinical phenomena. Res Nurs Health. 1990;13:227–236

 No author has a financial or proprietary interest in any material or method mentioned.

 Presented in part at the Nordic Congress of Ophthalmology, Tromsø, Norway, June 2008.

PII: S0886-3350(09)00400-3

doi: 10.1016/j.jcrs.2009.03.023

Journal of Cataract & Refractive Surgery
Volume 35, Issue 8 , Pages 1363-1366 , August 2009