Journal of Cataract & Refractive Surgery
Volume 35, Issue 8 , Pages 1358-1362 , August 2009

Complication and failure rates after corneal crosslinking

  • Tobias Koller, MD
    • ,
  • Michael Mrochen, PhD
    • ,
  • Theo Seiler, MD, PhD

      Affiliations

    • Corresponding Author InformationCorresponding author: Theo Seiler, MD, PhD, Institut für Refraktive und Ophthalmo-Chirurgie (IROC), Stockerstrasse 37, CH-8002 Zürich, Switzerland.

Received 20 December 2008 ,Revised 16 March 2009 ,Accepted 16 March 2009.

References 

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  2. Schnitzler E, Spörl E, Seiler T. Bestrahlung der Hornhaut mit UV-Licht und Riboflavingabe als neuer Behandlungsversuch bei einschmelzenden Hornhautprozessen, erste Ergebnisse bei vier Patienten. [Crosslinking of the corneal collagen by UV-radiation with Riboflavin for the mode of treatment melting ulcera of the cornea, first results of four patients]. Klin Monatsbl Augenheilkd. 2000;217:190–193
  3. Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620–627
  4. Caporossi A, Baiocchi S, Mazzotta C, Traversi C, Caporossi T. Parasurgical therapy for keratoconus by riboflavin-ultraviolet type A rays induced cross-linking of corneal collagen; preliminary refractive results in an Italian study. J Cataract Refract Surg. 2006;32:837–845
  5. Wittig-Silva C, Whiting M, Lamoureux E, Lindsay RG, Sullivan LJ, Snibson GR. A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results. J Refract Surg. 2008;24:S720–S725
  6. Koller T, Iseli HP, Hafezi F, Vinciguerra P, Seiler T. Scheimpflug imaging of corneas after collagen cross-linking. In press, Cornea 2009.
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  8. Hafezi F, Kanellopoulos J, Wiltfang R, Seiler T. Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2007;33:2035–2040
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  11. Seiler T, Hafezi F. Corneal cross-linking-induced stromal demarcation line. Cornea. 2006;25:1057–1059
  12. Eberwein P, Auw-Hädrich C, Birnbaum F, Maier PC, Reinhard T. Hornhauteinschmelzung nach Cross-Linking und tiefer lamellärer Keratoplastik (“DALK”) bei Keratokonus. [Corneal melting after cross-linking and deep lamellar keratoplasty in a keratoconus patient]. Klin Monatsbl Augenheilkd. 2008;225:96–98
  13. Mazzotta C, Balestrazzi A, Baiocchi S, Traversi C, Caporossi A. Stromal haze after combined riboflavin-UVA corneal collagen cross-linking in keratoconus: in vivo confocal microscopic evaluation. [letter] Clin Exp Ophthalmol. 2007;35:580–582
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  18. Raiskup-Wolf F, Hoyer A, Spoerl E, Pillunat LE. Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results. J Cataract Refract Surg. 2008;34:796–801
  19. Kanellopoulos J, Binder PS. Collagen cross-linking (CCL) with sequential topography-guided PRK; a temporizing alternative for keratoconus to penetrating keratoplasty. Cornea. 2007;26:891–895

 Dr. Mrochen has a financial interest in the UV-X device. No other author has a financial or proprietary interest in any material or method mentioned.

PII: S0886-3350(09)00481-7

doi: 10.1016/j.jcrs.2009.03.035

Journal of Cataract & Refractive Surgery
Volume 35, Issue 8 , Pages 1358-1362 , August 2009

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