Prospective evaluation of posterior capsule opacification in myopic eyes 4 years after implantation of a single-piece acrylic IOL
Received 9 March 2009; received in revised form 7 April 2009; accepted 13 April 2009.
Purpose
To determine whether axial myopia affects posterior capsule opacification (PCO) in eyes with high myopia (axial length [AL] ≥26.00 mm) 4 years after implantation of an AcrySof single-piece intraocular lens (IOL).
Setting
Clinical practice, Ahmedabad, India.
Methods
In a prospective masked trial, consecutive eyes with high axial myopia (myopia group) and age-matched eyes with a normal AL (21.00 to 23.99 mm) (control group) had phacoemulsification and in-the-bag IOL implantation. Postoperatively, PCO was documented by standardized digital retroillumination images. The PCO area behind the IOL optic was scored (scale 0% to 100%) using the POCO software system. The presence of PCO within the central 3.0 mm of the optic was assessed with the Evaluation of Posterior Capsule Opacification software system. The incidence of neodymium:YAG (Nd:YAG) capsulotomy was determined.
Results
The median PCO in the myopia group and control group, respectively, was 3.2% and 5.6% at 1 month (P = .2), 2.2% and 1.6% at 12 months (P = .079), 7.0% and 2.3% at 24 months (P = .079), 3.7% and 3.6% at 36 months (P = .78), and 10.0% and 2.3% at 48 months (P = .61). By 4 years, PCO had encroached onto the central 3.0 mm of the optic in 38% in the myopia group and 20% in the control group (P = .04). One eye (2%) in each group had an Nd:YAG capsulotomy, at 3.2 years and 3.9 years, respectively.
Conclusion
Axial myopia did not significantly increase the area or incidence of PCO at 4 years.
From the Iladevi Cataract & IOL Research Centre, Raghudeep Eye Clinic, Ahmedabad, India
Corresponding author: Abhay R. Vasavada, MS, FRCS, Iladevi Cataract & IOL Research Centre, Raghudeep Eye Clinic, Gurukul Road, Memnagar, Ahmedabad 380 052, India.
No author has a financial or proprietary interest in any material or method mentioned.
Jignasu Yagnik provided statistical assistance. Kaid Johar, MPhil, PhD, reviewed the manuscript. David J. Spalton, FRCS, analyzed the images.
ABSTRACT