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Volume 36, Issue 2, Pages 268-272 (February 2010)


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Ocular blood-flow hemodynamics before and after application of a laser in situ keratomileusis ring

Miriam L. Conway, PhDCorresponding Author Informationemail address, Mark Wevill, MD, Alexandra Benavente-Perez, PhD, Sarah L. Hosking, PhD

Received 16 January 2009; received in revised form 7 August 2009; accepted 3 September 2009.

Purpose

To evaluate blood-flow responses before and after microkeratome application.

Setting

School of Life and Health Sciences, Aston University, Birmingham, United Kingdom.

Methods

Hemodynamic responses were measured in eyes of healthy volunteers before and after transient elevation in intraocular pressure (IOP) resulting from microkeratome application. The IOP was elevated above 85 mm Hg for 90 seconds. Blood-flow responses were measured using color Doppler imaging, Heidelberg retinal flowmetry, and an ocular blood-flow analyzer.

Results

The study included 10 eyes. There was no difference in ocular-perfusion measurements before or after IOP elevation using any measurement system.

Conclusion

In normal healthy eyes, once suction was released, blood-flow responses returned immediately to normal levels.

Financial Disclosure

No author has a financial or proprietary interest in any material or method mentioned.

From the Department of Optometry and Visual Science (Conway, Hosking), City University, London, and Aston Academy of Life Sciences (Wevill), Aston University, Birmingham, United Kingdom; SUNY State College of Optometry (Benavente-Perez, Hosking), Biological Sciences, New York, New York, USA; Centre for Eye Research Australia (Hosking), Department of Ophthalmology, University of Melbourne, East Melbourne, Victoria, Australia

Corresponding Author InformationCorresponding author: Miriam Conway, PhD, Department of Optometry and Visual Science, City University, Northampton Square, London EC1V OHB, United Kingdom.

PII: S0886-3350(09)00984-5

doi:10.1016/j.jcrs.2009.09.013


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